What should I tell my health care provider before I take this medicine? They need to know if you have any of these conditions: * become easily dehydrated * diabetic ketoacidosis * heart disease * if you frequently drink alcohol containing drinks * kidney disease * liver disease * polycystic ovary syndrome * serious infection or injury * swelling of the arms, legs, or feet * undergoing surgery or certain x-ray procedures with injectable contrast agents * vomiting * an unusual or allergic reaction to metformin, pioglitazone, medicines, foods, dyes, or preservatives * pregnant or trying to get pregnant * breast-feeding metformin life extension metformin in new onset diabetes what is metformin hcl metformin and pcos metformin tablets